Can we mix two COVID-19 vaccines?


One big question on everybody’s mind is if we can mix two different COVID-19 vaccines doses.

A question on everyone’s mind: can you mix two different COVID-19 vaccines between your first and second dose? After all, vaccines aim for the same immunity. But of course, it’s way more complex than it seems. Not every vaccine works the same, in the end. For the first time, scientists are attempting to address the question. A new study out of the United Kingdom might be able to provide some answers soon.

The concept has been dubbed “mix and match”, because it involves giving a single person various combinations of licensed COVID-19 vaccines for the first and second doses. Matthew Snape, a professor at the University of Oxford, has focused on clarifying what we know so far. One of the main issues is vaccine supply, since we can’t be sure one single provider can answer an entire’s country demand.

“You’re not going to be able to control the supply in the first and second doses as well, perhaps, as some other countries,” stated Snape. “So these mixed schedules might well be the key to getting two doses into as many people in the world as possible.”

Research aims to identify whether it’s possible to combine different vaccines doses

The Oxford Vaccine Group launched the COM-COV research in February. The Group will release findings from the first phase of the research in the coming weeks. The study involved more than 800 volunteers over the age of 50. Experts say that taking several doses of different vaccines is effective, but the most critical question is whether the vaccines still function when combined.

But it’s about more than just combining vaccines to increase availability. The research in the United Kingdom may also decide if two separate shots yield better results than one brand alone. The study gave test subjects both AstraZeneca, which uses a cold virus to develop immunity, and Pfizer, which primes the immune system with messenger RNA. Moderna and Novavax were added to the list of vaccines that volunteers could receive when the study was extended in April. Both Pfzier and Moderna are more similar than other vaccines, since they are both mRNA vaccines.